Sugar… Aww Honey, Honey…

Sugar… Aww Honey, Honey…

How Sweetness can is bad (Part I):

Artificial Sweeteners

The next few posts will explain why I choose to eat raw sugar and natural sweeteners (and take the calories) over the manufactured stuff. Five artificial sweeteners are approved by the Food and Drug Administration: aspartame, saccharin, acesulfame-K, neotame, and sucralose. The agency regulates artificial sweeteners as food additives, which must be approved as safe before they can be marketed.

"The FDA evaluates a sweetener's composition and properties, how much of the substance is likely to be consumed, and various types of safety studies," says Laura Tarantino, Ph.D., director of the Office of Food Additive Safety in the FDA's Center for Food Safety and Applied Nutrition.

For each of the approved sweeteners, the typical amount used by U.S. consumers is well within designated "acceptable daily intake levels (ADI)," or levels that can be consumed safely every day over a lifetime. Here's a detailed look at each of the sweeteners.

Aspartame is 200 times sweeter than sugar. It has a caloric value similar to sugar (4 kcal/g), but the amounts used are small enough to consider aspartame essentially free of calories. Brand names include NutraSweet and Equal. Aspartame was first approved by the FDA in 1981 as a tabletop sweetener, and for use in gum, breakfast cereal, and other dry products. The use of aspartame was expanded to sodas in 1983, and then to use as a general-purpose sweetener in all foods and drinks in 1996.

Before approval, the FDA reviewed numerous studies showing that aspartame did not cause cancer or other adverse effects in laboratory animals. "This included three studies in which rats were fed aspartame in proportions more than 100 times higher than humans would likely consume.

Science costs money, and who you know: The FDA's federal budget request for 2008 totaled $2.1 billion, a $105.8 million increase from what it received in 2007.

FDA is also funded by user fees submitted with New Drug Applications under the Prescription Drug User Fee Act (PDUFA) in which the industry pays a fee for the review of the new product. A similar process is used for medical devices under the Medical Device User Fee and Modernization Act (MDUFMA) and for animal drugs under a similar act.

Sweet choices: The Food and Drug Administration (FDA) has approved five low-calorie sweeteners for use in a variety of foods. The FDA has established an "acceptable daily intake" (ADI) for each sweetener. This is the maximum amount considered safe to consume each day if your normal body weight should be at least 150 lbs.

Artificial sweetener	ADI*	Estimated ADI equivalent**	OK for cooking?
Aspartame (NutraSweet, Equal)	50 milligrams (mg) per kilogram (kg)	18 to 19 cans of diet cola	No
Saccharin (Sweet'N Low, SugarTwin)	5 mg per kg	9 to 12 packets of sweetener	Yes
Acesulfame K (Sunett, Sweet One)	15 mg per kg	30 to 32 cans of diet lemon-lime soda***	Yes
Sucralose (Splenda)	5 mg per kg	6 cans of diet cola***	Yes
Neotame	18 mg a day	No consumer products available yet in the U.S.	Yes

*FDA-established acceptable daily intake (ADI) limit per kilogram (2.2 pounds) of body weight.
**Product-consumption equivalent for a 150-pound person.
***These products usually contain more than one type of sweetener.

Be careful when choosing artificial sweeteners, such as aspartamane, sucrolose and malitol. Many are safe, but some artificial sweeteners have been linked to increased cancer risk. Limit your use of them. The unfortunate reality is that many artificial sweeteners were at first thought to be healthy, but studies later indicated that they may have serious health consequences. Most of these tests have been inconclusive, most have not been conducted with humans and further studies are ongoing. But if there is a question about a sweetener's side effects, you are, in effect, playing the role of guinea pig until more conclusive evidence surfaces. If you're concerned about artificial sweeteners, opt for natural alternatives.